Jessica Kandel, MD

Surgeon-in-Chief, The University of Chicago Medicine Comer Children's Hospital
Chief, Section of Pediatric Surgery

Jessica Kandel

Jessica J. Kandel, MD, is an expert in pediatric surgery. She specializes in the treatment of pediatric cancers, including Wilms tumor, neuroblastoma and hepatoblastoma, as well as vascular anomalies (hemangiomas, venous malformations, lymphatic malformations).

Dr. Kandel's research focuses on the development and differentiation of blood vessels (angiogenesis) in solid tumors and vascular anomalies. She was a leader in early studies that suppressed tumor growth by blocking vascular endothelial growth factor, a protein that stimulates angiogenesis. Dr. Kandel's work contributed to the development of bevacizumab, a drug used to manage metastatic colorectal, lung, and kidney cancers.

As the primary investigator on several long-term studies, Dr. Kandel's current goal is to understand how tumors become resistant to therapies in order to identify new treatments for refractory cancers. Her research has been funded by notable organizations including the National Cancer Institute, the American Cancer Society, and the Pediatric Cancer Foundation.

Dr. Kandel has contributed widely to medical literature, publishing more than 60 peer-reviewed articles and three book chapters on angiogenesis and tumor growth. She currently serves as an editor for Oncology Letters and as an ad hoc reviewer for several other scientific journals. In addition, Dr. Kandel is a popular speaker and a dedicated educator, mentoring medical students, residents, and fellows on a range of research projects related to tumor modeling.

Practice Locations

The University of Chicago Medicine 
5841 S. Maryland Avenue 
Chicago, IL 60637

The University of Chicago Medicine 
Comer Children's Hospital 
5721 S. Maryland Avenue 
Chicago, IL 60637

Year Started Practice


Board Certifications

General Surgery 
Pediatric Surgery

Medical School

Columbia University College of Physicians and Surgeons

Internship and Residency

Massachusetts General Hospital, Boston


Pediatric Surgical Research Laboratories, Boston Children’s Hospital 
Johns Hopkins Hospital, Baltimore


American Academy of Pediatrics 
American College of Surgeons 
American Pediatric Surgical Association 
American Surgical Association 
Children’s Oncology Group 
International Society of Paediatric Surgical Oncology 
National Wilms Tumor Study Group 
Pediatric Board of the American Board of Surgery 
Society of Surgical Oncology 
Society of University Surgeons

Language Spoken



Office Phone

(773) 702-6175

Office Fax

(773) 702-1192

Office Postal Address

Jessica J. Kandel, MD 
The University of Chicago Medicine 
5841 S. Maryland Avenue, MC 4062 
Chicago, IL 60637